Handbook of Pharmaceutical Granulation Technology Free Download
DESCRIPTION
Integrating the basic principles and industrial practices of pharmaceutical granulation production, this book discusses technologies and demonstrates cost-effective approaches to manufacturing solid-dosage forms with content uniformity and consistent physical properties while complying with regulatory requirements. Specialists from pharmaceutical companies, academia, and the U.S. Drug Regulatory Affairs agency address current and changing practices in industrial drug granulation production. Text, charts, figures, and photographs illustrate the pros and cons of diverse methods and technologies for accurately achieving strong bonding of particles in tablets and capsules
Introduction, D. M. Parikh
Theory of Granulation, L.L. Augsburger and M.K. Vuppala
Drug Substance and Excipient Characterization, P.W.S. Heng and L.W.Chan
Binders and Solvents, R.K. Khankari and J. Hontz
Spray Drying as an Alternative Granulation Technique, F.V. Shaw
Roller Compaction Technology, R.W. Miller
High Shear Mixer Granulators, P. Holm
Low Shear Granulators, T. Chirkot and C. W. Propst
Batch Fluid Bed Granulation, D.M. Parikh, J.A. Bonck, and M. Mogavero
Single-Pot Processing, T.P. Garcia and L.J. Lucisano
Extrusion-Spheronization as a Granulation Technique, D.F. Erkoboni
Continuous Granulation, M. Bonde
Sizing of Granulation, G. S. Rekhi and M.K. Vuppala
Granulation Characterization: Methods and Significance, C.M. Sinko
Bioavailability and Granule Properties, S.S. Jambhekar
Regulatory Issues in Granulation Processes, G.A. Hileman
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